PUBLICATIONS

  1. Nguyen TD, Rao MK, Dhyani SP, Banks JM, Winek MA, Michalkiewicz J, Lee MY. Nucleoporin93 (Nup93) limits Yap activity to prevent endothelial cell senescence and dysfunction. Aging Cell. 2024 Feb 13:e14095. doi: 10.1111/acel.14095.

  2. Boutagy NE, Gamez-Mendez A, Fowler JWM, Zhang H, Chaube BK, Esplugues E, Kuo A, Lee S, Horikami D, Zhang J, Citrin KM, Singh AK, Coon BG, Lee MY, Suarez Y, Fernandez-Hernando C, Sessa WC. Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice. J Clin Invest. 2024 Jan 4. e170453. doi: 10.1172/JCI170453.

  3. Nguyen TD, Rahman N, Sessa WC, Lee MY. Endothelial Nitric Oxide Synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation. Front Cardiovasc Med. 2023 October 11. doi: 10.3389/fcvm.2023.1279868

  4. Hyun J, Lee MY, Rehman J, Pajcini KV, Malik AB. Notch1 Promotes Revascularization through Modulation of Downstream Vascular Patterning Signaling. J Physiol. 2021 Dec 17; doi: 10.1113/JP282286.

  5. Lee MY, Gamez-Mendez A, Zhang J, Zhuang Z, Vinyard DJ, Kraehling J, Velazquez H, Brudvig GW, Kyriakides TR, Simons M, Sessa WC. Endothelial Akt1-dependent activation of eNOS is critical for vascular tone regulation and vessel remodeling. Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):870-879. doi: 10.1161/ATVBAHA.118.310748.

  6. Kuo A, Lee MY, Yang K, Gross, RW, Sessa, WC. Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin stimulated cAMP-mediated lipolysis. J Biol Chem. 2018 Jan 19;293(3):973-983. doi: 10.1074/jbc.RA117.000980.

  7. Protack C, Foster T, Hashimoto T, Yamamoto K, Lee MY, Kraehling J, Bai H, Hu H, Santana J, Wang M, Sessa WC, and Dardik A. Eph-B4 regulates flow dependent venous remodeling and improves arteriovenous fistula patency. Sci Rep. 2017 Nov 13;7(1):15386. doi: 10.1038/s41598-017-13071-2.

  8. Jin Y, Xie Y, Ostriker AC, Zhang X, Liu R, Lee MY, Leslie KL, Tang W, Du J, Lee SH, Wang Y, Sessa WC, Hwa J, Yu J, Martin KA. Opposing actions of AKT isoforms in vascular smooth muscle injury and therapeutic response. Arterioscler Thromb Vasc Biol. 2017 Oct 12. pii: ATVBAHA.117.310053. doi: 10.1161/ATVBAHA.117.310053.

  9. Nakamura T, Fujiwara Y, Yamada R, Fujii W, Hamabata T, Lee MY, Maeda S, Aritake K, Roers A, Sessa WC, Nakamura M, Urade Y, Murata T. Mast cell-derived prostaglandin D2 attenuates anaphylactic reactions in mice. J Allergy Clin Immunol. 2017 Apr 22. pii: S0091-6749(17)30476-1. doi: 10.1016/j.jaci.2017.02.030.

  10. Kuo A, Lee MY, Sessa WC. Lipid Droplet Biogenesis and Function in the Endothelium. Circ Res. 2017 Apr 14;120(8):1289-1297. doi:10.1161/CIRCRESAHA.116.310498. Epub 2017 Jan 24

  11. Ola R, Dubrac A, Han J, Zhang F, Fang JS, Larrivée B, Lee MY, Urarte AA, Kraehling JR, Genet G, Hirschi KK, Sessa WC, Canals FV, Graupera M, Yan M, Young LH, Oh PS, Eichmann A. PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia. Nat Commun. 2016 Nov 29;7:13650. doi: 10.1038/ncomms13650.

  12. Kraehling JR, Chidlow JH, Rajagopal C, Sugiyama MG, Fowler JW, Lee MY, Zhang X, Ramírez CM, Park EJ, Tao B, Chen K, Kuruvilla L, Larriveé B, Folta-Stogniew E, Ola R, Rotllan N, Zhou W, Nagle MW, Herz J, Williams KJ, Eichmann A, Lee WL, Fernández-Hernando C, Sessa WC. Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells. Nat Commun. 2016 Nov 21;7:13516. doi: 10.1038/ncomms13516.

  13. Kraehling JR, Hao Z, Lee MY, Vinyard DJ, Velazquez H, Liu X, Stan RV, Brudvig GW, Sessa WC. Uncoupling Caveolae From Intracellular Signaling In Vivo. Circ Res. 2016 Jan 8;118(1):48-55. doi: 10.1161/CIRCRESAHA.115.307767.

  14. Chamorro-Jorganes A, Lee MY, Araldi E, Landskroner-Eiger S, Fernández-Fuertes M, Sahraei M, Quiles Del Rey M, van Solingen C, Yu J, Fernández-Hernando C, Sessa WC, Suárez Y. VEGF-Induced Expression of miR-17-92 Cluster in Endothelial Cells Is Mediated by ERK/ELK1 Activation and Regulates Angiogenesis. Circ Res. 2016 Jan 8;118(1):38-47. doi: 10.1161/CIRCRESAHA.115.307408.

  15. Landskroner-Eiger S, Qiu C, Perrotta P, Siragusa M, Lee MY, Ulrich V, Luciano AK, Zhuang ZW, Corti F, Simons M, Montgomery RL, Wu D, Yu J, Sessa WC. Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling. Proc Natl Acad Sci. 2015 Oct 13;112(41):12812-7. doi: 10.1073/pnas.1507094112.

  16. Bancroft T, Bouaouina M, Roberts S, Lee MY, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR. Upregulation of Thrombospondin-2 in Akt1-null Mice Contributes to Compromised Tissue Repair due to Abnormalities in Fibroblast Function. J Biol Chem. 2015 Jan 2;290(1):409-22. doi: 10.1074/jbc.M114.618421.

  17. Lee MY, Luciano AK, Ackah E, Rodriguez-Vita J, Bancroft TA, Eichmann A, Simons M, Kyriakides TR, Morales-Ruiz M, Sessa WC. Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates. Proc Natl Acad Sci. 2014 Sep 2;111(35):12865-70. doi: 10.1073/pnas.140847.

  18. Lee MY, Skoura A, Park EJ, Landskroner-Eiger S, Jozsef L, Luciano AK, Murata T, Pasula S, Dong Y, Bouaouina M, Ferguson SM, Calderwood DA, De Camilli P, Sessa WC. Dynamin2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development. 2014. 141, 1465-1472. doi: 10.1242/dev.104539.

  19. Lohman AW, Billaud M, Straub AC, Johnstone SR, Best AK, Lee MY, Barr K, Penuela S, Laird DW, Isakson BE. Expression of pannexin isoforms in the systemic murine arterial network. J Vasc Res. 2012; 49:405-416. doi: 10.1159/000338758.

  20. Straub AC, Lohman AW, Billaud M, Johnstone SR, Dwyer ST, Lee MY, Shoppee Bortz P, Best AK, Columbus L, Gaston B, Isakson BE. Endothelial cell expression of hemoglobin α regulates nitric oxide signaling. Nature. 2012; 491, 473-477. doi: 10.1038/nature11626.

  21. Lee MY, Garvey SM, Ripley ML, Wamhoff BR. Genome-wide microarray analyses identify the Protein C Receptor (PROCR/EPCR) as a novel Cn/NFAT-dependent gene in vascular smooth muscle cell phenotypic modulation. Arterioscler Thromb Vasc Biol. 2011 Nov; 31(11):2665-75. doi: 10.1161/ATVBAHA.111.235960.

  22. Kadl A, Meher AK, Sharma PR, Lee MY, Doran AC, Elliot MR, Gruber F, Han J, Chen W, Kensler T, Ravichandran KS, Isakson BE, Wamhoff BR, Leitinger N. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circ Res. 2010 Sep 17; 107(6):737-46. doi: 10.1161/CIRCRESAHA.109.215715.

  23. Lee MY, Garvey SM, Baras AS, Lemmon JA, Gomez MF, Daum G, LeBoeuf RC, Schoppee Bortz PD, Wamhoff BR. Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells. Hum Mol Genet. 2010 Feb 1;19(3):468-79. doi: 10.1093/hmg/ddp511.

  24. Long X, Tharp DL, Georger MA, Slivano OJ, Lee MY, Wamhoff BR, Bowles DK, Miano JM. The smooth muscle cell-restricted KCNMB1 ion channel subunit is a direct transcriptional target of serum response factor and myocardin. J Biol Chem. 2009 Nov 27;284(48):33671-82. doi: 10.1074/jbc.M109.050419.

  25. Hastings NE, Feaver RE, Lee MY, Wamhoff BR, Blackman BR.  Human IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow. Arterioscler Thromb Vasc Biol. 2009 May;29(5):725-31. doi: 10.1161/ATVBAHA.109.184382.

  26. Orr AW, Lee MY, Lemmon JA, Yurdagul A Jr, Gomez MF, Schoppee-Bortz PD, Wamhoff BR. Molecular mechanisms of collagen isotype-specific modulation of smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol. 2009 Feb;29(2):225-31. doi: 10.1161/ATVBAHA.108.178749.